Publications

Luke CJ, Markovina S, Good M, Wight IE, Thomas BJ, Linneman JM, Lanik WE, Koroleva O, Coffman MR, Miedel MT, Gong Q, Andress A, Campos Guerrero M, Wang S, Chen L, Beatty WL, Hausmann KN, White FV, Fitzpatrick JAJ, Orvedahl A, Pak SC, Silverman GA. Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins. Commun Biol. 2022 Jan 12;5(1):47. doi: 10.1038/s42003-021-02953-x. PMID: 35022507.

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Sanders J, Castiglione M, Shun TY, Vollmer L, Schurdak ME, Vogt A, Schwacha. Validation of a High Throughput Screening Assay to Identify Small Molecules that Target the Eukaryotic Replicative Helicase. SLAS Discovery, 2022. DOI: 10.1016/j.slasd.2021.12.006. PubMed PMID: 35058181.

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Saydmohammed M, Jha A, Mahajan V, Gavlock D, Shun TY, DeBiasio R, Lefever D, Li X, Reese C, Kershaw EE, Yechoor V, Behari J, Soto-Gutierrez A, Vernetti L, Stern A, Gough A, Miedel MT, Lansing Taylor D (2021) Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors. Experimental biology and medicine; 246(22):2420-41. Epub 2021/05/08. PubMed PMID: 33957803.

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Ji B, Xue Y, Xu Y, Liu S, Gough AH, Xie XQ, Wang J (2021) Drug-Drug Interaction Between Oxycodone and Diazepam by a Combined in Silico Pharmacokinetic and Pharmacodynamic Modeling Approach. ACS chemical neuroscience; 12(10):1777-90. Epub 2021/05/06. PubMed PMID: 33950681.

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Saydmohammed M, Jha A, Mahajan V, Gavlock D, Shun TY, DeBiasio R, Lefever D, Li X, Reese C, Kershaw EE, Yechoor V, Behari J, Soto-Gutierrez A, Vernetti L, Stern A, Gough A, Miedel MT*, Lansing Taylor D*. Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors. Exp Biol Med (Maywood). 2021 May 6:15353702211009228. doi: 10.1177/15353702211009228. Epub ahead of print. PMID: 33957803. [* senior author]

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Sannino S, Yates ME, Schurdak ME, Oesterreich S, Lee AV, Wipf P, Brodsky JL. Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised. eLife. 2021;10. Epub 2021/06/29. doi: 10.7554/eLife.64977. PubMed PMID: 34180400; PMCID: PMC8275131.

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Bircsak KM, DeBiasio R, Miedel M, Alsebahi A, Reddinger R, Saleh A, Shun T, Vernetti LA, Gough A (2021) A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®. Toxicology; 450:152667. Epub 2020/12/29. PubMed PMID: 33359578.

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Sakolish C, Reese CE, Luo YS, Valdiviezo A, Schurdak ME, Gough A, Taylor DL, Chiu WA, Vernetti LA, Rusyn I (2021) Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS). Toxicology; 448:152651. Epub 2020/12/12. PubMed PMID: 33307106.

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Schurdak M, Vernetti L, Bergenthal L, Wolter QK, Shun TY, Karcher S, Taylor DL, Gough A (2020) Applications of the microphysiology systems database for experimental ADME-Tox and disease models. Lab on a chip; 20(8):1472-92. Epub 2020/03/27. PubMed PMID: 32211684.

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Miedel MT, Gavlock DC, Jia S, Gough A, Taylor DL, Stern AM. Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System. Sci Rep. 2019 Jun 6;9(1):8341. doi: 10.1038/s41598-019-44756-5. PMID: 31171849.

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