A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics. Ngo M, Wechter N, Tsai E, Shun TY, Gough A, Schurdak ME, Schwacha A and Vogt A (2019) SLAS Discov;24(6):669-81. Epub 2019/02/26. doi: 10.1177/2472555219829740. PubMed PMID: 30802412.
Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System. Miedel MT, Gavlock DC, Jia S, Gough A, Taylor DL and Stern AM (2019) Scientific reports;9(1):8341. Epub 2019/06/07. doi: 10.1038/s41598-019-44756-5. PubMed PMID: 31171849.
Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision. Kochanek PM, Jackson TC, Jha RM, Clark RSB, Okonkwo DO, Bayir H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, Puccio AM, Horvat CM, Au AK, Elmer J, Treble-Barna A, Ikonomovic MD, Shutter LA, Taylor DL, Stern AM, Graham SH, Kagan VE, Jackson EK, Wisniewski SR and Dixon CE (2019) J Neurotrauma. Epub 2018/12/07. doi: 10.1089/neu.2018.6203. PubMed PMID: 30520681.
GP78 Cooperates with Dual-Specificity Phosphatase 1 To Stimulate Epidermal Growth Factor Receptor-Mediated Extracellular Signal-Regulated Kinase Signaling. Kho DH, Uddin MH, Chatterjee M, Vogt A, Raz A and Wu GS (2019) Mol Cell Biol;39(11). Epub 2019/05/08. doi: 10.1128/mcb.00485-18. PubMed PMID: 31061093.
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevilla C, Starkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA and Bataller R (2019) Nature communications;10(1):3126. Epub 2019/07/18. doi: 10.1038/s41467-019-11004-3. PubMed PMID: 31311938.
PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy. Abecassis I, Sedgewick AJ, Romkes M, Buch S, Nukui T, Kapetanaki MG, Vogt A, Kirkwood JM, Benos PV and Tawbi H (2019) Scientific reports;9(1):3309. Epub 2019/03/03. doi: 10.1038/s41598-019-39542-2. PubMed PMID: 30824778.
A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes. Schurdak ME, Pei F, Lezon TR, Carlisle D, Friedlander R, Taylor DL and Stern AM (2018) Methods Mol Biol;1787:207-22. Epub 2018/05/08. doi: 10.1007/978-1-4939-7847-2_16. PubMed PMID: 29736721.
A High-Content Screen Reveals New Small-Molecule Enhancers of Ras/Mapk Signaling as Probes for Zebrafish Heart Development. Saydmohammed M, Vollmer LL, Onuoha EO, Maskrey TS, Gibson G, Watkins SC, Wipf P, Vogt A and Tsang M (2018) Molecules;23(7). Epub 2018/07/13. doi: 10.3390/molecules23071691. PubMed PMID: 29997348.
A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX. Li X, George SM, Vernetti L, Gough AH and Taylor DL (2018) Lab Chip;18:2614-31. doi: 10.1039/C8LC00418H. PubMed PMID: 30063238.
Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation. Keating SM, Taylor DL, Plant AL, Litwack ED, Kuhn P, Greenspan EJ, Hartshorn CM, Sigman CC, Kelloff GJ, Chang DD, Friberg G, Lee JSH and Kuida K (2018) Clin Transl Sci;11(3):267-76. Epub 2018/03/03. doi: 10.1111/cts.12536. PubMed PMID: 29498218.