Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes. Jia S, Miedel MT, Ngo M, Hessenius R, Chen N, Wang P, Bahreini A, Li Z, Ding Z, Shun TY, Zuckerman DM, Taylor DL, Puhalla SL, Lee AV, Oesterreich S and Stern AM (2018) Oncology;94(3):176-89. Epub 2018/01/08. doi: 10.1159/000485510. PubMed PMID: 29306943.
Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies. Gough A, Shun TY, Taylor DL and Schurdak M (2018) Methods Mol Biol;1745:25-46. Epub 2018/02/25. doi: 10.1007/978-1-4939-7680-5_2. PubMed PMID: 29476461.
Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells. Chakraborty S, Jiang C, Gau D, Oddo M, Ding Z, Vollmer L, Joy M, Schiemann W, Stolz DB, Vogt A, Ghosh S and Roy P (2018) Br J Cancer;119(9):1106-17. Epub 2018/10/16. doi: 10.1038/s41416-018-0284-6. PubMed PMID: 30318519.
Liver ‘organ on a chip’. Beckwitt CH, Clark AM, Wheeler S, Taylor DL, Stolz DB, Griffith L and Wells A (2018) Exp Cell Res;363(1):15-25. Epub 2018/01/02. doi: 10.1016/j.yexcr.2017.12.023. PubMed PMID: 29291400.
New insights into shear stress-induced endothelial signalling and barrier function: cell-free fluid versus blood flow. Xu S, Li X, LaPenna KB, Yokota SD, Huke S and He P (2017) Cardiovascular research;113(5):508-18. Epub 2017/02/06. doi: 10.1093/cvr/cvx021. PubMed PMID: 28158679.
Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP and Taylor DL (2017) Scientific reports;7:42296. doi: 10.1038/srep42296. PubMed PMID: 28176881.
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release. Suofu Y, Li W, Jean-Alphonse FG, Jia J, Khattar NK, Li J, Baranov SV, Leronni D, Mihalik AC, He Y, Cecon E, Wehbi VL, Kim J, Heath BE, Baranova OV, Wang X, Gable MJ, Kretz ES, Di Benedetto G, Lezon TR, Ferrando LM, Larkin TM, Sullivan M, Yablonska S, Wang J, Minnigh MB, Guillaumet G, Suzenet F, Richardson RM, Poloyac SM, Stolz DB, Jockers R, Witt-Enderby PA, Carlisle DL, Vilardaga JP and Friedlander RM (2017) Proceedings of the National Academy of Sciences of the United States of America;114(38):E7997-e8006. Epub 2017/09/07. doi: 10.1073/pnas.1705768114. PubMed PMID: 28874589.
Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images. Spagnolo DM, Al-Kofahi Y, Zhu P, Lezon TR, Gough A, Stern AM, Lee AV, Ginty F, Sarachan B, Taylor DL and Chennubhotla SC (2017) Cancer Res;77(21):e71-e4. Epub 2017/11/03. doi: 10.1158/0008-5472.can-17-0676. PubMed PMID: 29092944.
Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy. Vernetti LA, Vogt A, Gough A and Taylor DL (2017) Clin Liver Dis;21(1):197-214. Epub 2016/11/16. doi: 10.1016/j.cld.2016.08.013. PubMed PMID: 27842772.
Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems. Soto-Gutierrez A, Gough A, Vernetti LA, Taylor DL and Monga SP (2017) Exp Biol Med (Maywood):1535370217707731. Epub 2017/05/04. doi: 10.1177/1535370217707731. PubMed PMID: 28467181.