Funding Announcement: Drs. D. Lansing Taylor, Mark Miedel, Alejandro Soto-Gutierrez, Mark Schurdak, and Lawrence Vernetti have received funding from NCATS for a five year grant establishing one of four Translational Centers for MPS (TraCe). This award is a collaborative effort with both NCATS and the FDA focused on qualifying our patient-derived biomimetic liver MPS as drug discovery tools in multiple Contexts of Use including drug metabolism, toxicity, drug efficacy testing and clinical trial cohort selection.